TubeBuddy does a lot. Probably more than most people need. For that reason, we recommend turning off features that you are not using because they can potentially slow down your experience on YouTube.
To do so, click on the Settings link from the main TubeBuddy menu.
Then check/un-check items and click Save Changes. When you go back to YouTube and refresh the page, the changes will take effect.
Please note that one particular feature that you can't turn on/off from the main settings area is the Quick-Edit Toolbar. To turn this off, click on the settings icon on the tool itself, then click "Hide Quick Edit Toolbar"